Characterisation of Shigella species isolated from river catchments in the North West province of South Africa

The occurrence and distribution of Shigella species in water from the five river catchments in the North West province of South Africa were investigated.Shigella is a Gram-negative, non-motile, facultative anaerobic bacillus that causes shigellosis, an important cause of morbidity and mortality in high-risk populations (such as children, the elderl

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Implementing community based inclusive development for people with disability in Latin America: a mixed methods perspective on prioritized needs and lessons learned

Abstract Background Research on the needs of people with disability is scarce, which promotes inadequate programs.Community Based Inclusive Development interventions aim to promote rights but demand a high level of community participation.This study aimed to identify prioritized needs as well as lessons learned for successful project implementation

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Computational methods for detecting cancer hotspots

Cancer mutations that are recurrently observed among patients are known as hotspots.Hotspots are highly relevant because they are, presumably, likely functional.Known hotspots in BRAF, PIK3CA, TP53, KRAS, IDH1 support this idea.However, hundreds of hotspots have never been validated experimentally.The detection of hotspots nevertheless Bare End Pow

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